I call BS & beside, not relevant now as no vax is effective against current strains & more vaccines = more risk of infection & more serious infection; try to keep up.
I call BS & beside, not relevant now as no vax is effective against current strains & more vaccines = more risk of infection & more serious infection; try to keep up.
I call BS too. Based on an understanding of immunology, the primary response to a respiratory infection is mucosal: Tcell and NKcell immunity (in addition to non-specific, igA secretory antibodies). This broad immune memory is built during lifelong exposure to other similar glycosylated viruses (including other coronaviruses) and is based on the recognition of non-structural proteins (not spike) expressed early during infection. These proteins are shared across a wide variety of viruses including SARS cov-2. As such mRNA transfections CANNOT simply take credit for preventing viremia or severe infection when the antibodies they elicit are systemic not mucosal. Any T-cell memory the transfections also elicit are also ONLY to the spike and not broad enough to be capable of stopping the various mutations that occur. The simple fact is that in most people ('vaxxed' or not), the mucosal immune response/memory is perfectly capable (asymptomatically or symptomatically) of dealing with an infection without it ever progressing further.
It's quite frankly horseshit and a stretch for PHE to give credit to the transfections when the real hero is a highly sophisticated immune system which may need support during infection but cannot be better augmented by mRNA transfection.
Hawaii existsтАжand millions of Covid infected mainlanders have been visiting it the last 12 months and the state hasnтАЩt been ravaged by Covid. The vaccine did what it was supposed to which is protect those that got it and it isnтАЩt dangerous.
Get this into your head once and for all. The data on Hawaii or elsewhere is IRRELEVANT to the mechanism of action. mRNA transfection only stimulate humoral antibodies NOT mucosal antibodies. There is ZERO evidence these can cross the lung barrier. Thus if a vaxxed person does not get systemic viremia you CANNOT ascribe that to the efficacy humoral antibodies without evidence. The mucosal immune system takes care of most infections in these people not the transfection. Go read some basic immunology. This was well known until 2020 when "the science" came along. By all means if you want to keep getting your boosters that's your prerogative, but leave the rest of us alone.
Pathetic. COVID ravaged nothing except a narrow group of the highly susceptible that had preexisting comorbidities. Otherwise it had a fatality rate similar to the seasonal flu. On the other hand, the faux-vaccine has done and continues to do massive damage.
So? The vaccine mitigated severity through Delta and if it was dangerous excess deaths in highly vaccinated populations would be high. Hawaii shows that vaccinated immunity is fine and that it was dangerous to go for natural immunity.
I call BS & beside, not relevant now as no vax is effective against current strains & more vaccines = more risk of infection & more serious infection; try to keep up.
I call BS too. Based on an understanding of immunology, the primary response to a respiratory infection is mucosal: Tcell and NKcell immunity (in addition to non-specific, igA secretory antibodies). This broad immune memory is built during lifelong exposure to other similar glycosylated viruses (including other coronaviruses) and is based on the recognition of non-structural proteins (not spike) expressed early during infection. These proteins are shared across a wide variety of viruses including SARS cov-2. As such mRNA transfections CANNOT simply take credit for preventing viremia or severe infection when the antibodies they elicit are systemic not mucosal. Any T-cell memory the transfections also elicit are also ONLY to the spike and not broad enough to be capable of stopping the various mutations that occur. The simple fact is that in most people ('vaxxed' or not), the mucosal immune response/memory is perfectly capable (asymptomatically or symptomatically) of dealing with an infection without it ever progressing further.
It's quite frankly horseshit and a stretch for PHE to give credit to the transfections when the real hero is a highly sophisticated immune system which may need support during infection but cannot be better augmented by mRNA transfection.
Thanks for the deep dive into the immunology of the failure of the mRNA fiasco
Hawaii existsтАжand millions of Covid infected mainlanders have been visiting it the last 12 months and the state hasnтАЩt been ravaged by Covid. The vaccine did what it was supposed to which is protect those that got it and it isnтАЩt dangerous.
Get this into your head once and for all. The data on Hawaii or elsewhere is IRRELEVANT to the mechanism of action. mRNA transfection only stimulate humoral antibodies NOT mucosal antibodies. There is ZERO evidence these can cross the lung barrier. Thus if a vaxxed person does not get systemic viremia you CANNOT ascribe that to the efficacy humoral antibodies without evidence. The mucosal immune system takes care of most infections in these people not the transfection. Go read some basic immunology. This was well known until 2020 when "the science" came along. By all means if you want to keep getting your boosters that's your prerogative, but leave the rest of us alone.
Scoreboard!
Pathetic. COVID ravaged nothing except a narrow group of the highly susceptible that had preexisting comorbidities. Otherwise it had a fatality rate similar to the seasonal flu. On the other hand, the faux-vaccine has done and continues to do massive damage.
So? The vaccine mitigated severity through Delta and if it was dangerous excess deaths in highly vaccinated populations would be high. Hawaii shows that vaccinated immunity is fine and that it was dangerous to go for natural immunity.
"The vaccine mitigated severity through Delta..." Nope.